Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae

Abstract Background Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes.A DIVA subunit vaccine comprised of detergent-released proteins from A.pleuropneumoniae serotypes 1, 2 and 5 has been developed and shown to protect pigs

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Diagnostic accuracy of cardiovascular magnetic resonance imaging for assessment of right ventricular morphology and function in pulmonary artery hypertension

Background and objective: Assessment of RV function is complex and no single measurement is generally accepted in clinical practice, so PH is often diagnosed at a late stage of the disease, and is associated with poor survival.Cardiovascular magnetic resonance (CMRI) has become accepted as the gold standard technique for the assessment of the proxi

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Developing patient-centered outcomes research infrastructure in a rural community through patient and stakeholder engagement and education during the COVID-19 pandemic

In addition to facing numerous healthcare disparities, rural America is chronically underrepresented in clinical research.This gap was made more evident during the COVID-19 pandemic.St Lawrence Health, located in rural Upstate New York, established its Clinical and Rural Health Research Department in 2015 multimatic 255 tig kit to help close this g

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